tacrolimus(Prograf, Astagraf XL, Envarsus XR)
Calcineurin inhibitor (immunosuppressant)
Pronunciation
/tæˈkrɒlɪməs/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- tacrolimus
- Brand names
- Prograf, Astagraf XL, Envarsus XR, Protopic (topical)
- Therapeutic class
- Calcineurin inhibitor (immunosuppressant)
- Mechanism (summary)
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Clinical pearls
- Take twice daily, same time, on empty stomach (Prograf) - 1h before or 2h after food.
- Astagraf XL/Envarsus XR are NOT interchangeable with Prograf - confirm formulation at each refill.
- Avoid grapefruit juice and St John's wort.
- Use sunscreen - skin cancer risk.
- Get all vaccinations BEFORE starting; avoid live vaccines after.
Related drugs in this class
Sources
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