rituximab(Rituxan, Truxima, Ruxience)
Anti-CD20 monoclonal antibody (chimeric)
Pronunciation
/rɪˈtʊksɪmæb/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- rituximab
- Brand names
- Rituxan, Truxima, Ruxience
- Therapeutic class
- Anti-CD20 monoclonal antibody (chimeric)
- Mechanism (summary)
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Clinical pearls
- IV infusion in clinic; first infusion slowest with monitoring.
- Premedicate with acetaminophen + diphenhydramine.
- Screen for HBV before first dose; vaccinate if appropriate.
- Avoid live vaccines during and several months after.
- Report fever, new neurologic symptoms (PML), severe rash.
Sources
See how rituximab appears in NAPLEX-style questions
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