ondansetron(Zofran, Zofran ODT, Zuplenz)
Serotonin 5-HT3 receptor antagonist (antiemetic)
Pronunciation
/ɒnˈdænsɪtrɒn/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- ondansetron
- Brand names
- Zofran, Zofran ODT, Zuplenz
- Therapeutic class
- Serotonin 5-HT3 receptor antagonist (antiemetic)
- Mechanism (summary)
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Clinical pearls
- ODT: place on tongue and let dissolve - no water needed.
- Constipation may occur - increase fluids and fiber.
- Report fast or irregular heartbeat, fainting.
- Report confusion, fever, sweating, twitching (serotonin syndrome).
- Avoid in known long QT or with other QT-prolonging drugs unless necessary.
Sources
See how ondansetron appears in NAPLEX-style questions
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