ledipasvir/sofosbuvir(Harvoni)
HCV NS5A inhibitor + NS5B polymerase inhibitor (DAA)
Pronunciation
/lɛˈdɪpəzvɪr/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- ledipasvir/sofosbuvir
- Brand names
- Harvoni
- Therapeutic class
- HCV NS5A inhibitor + NS5B polymerase inhibitor (DAA)
- Mechanism (summary)
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Clinical pearls
- Take once daily with or without food at the same time each day.
- Adhere to full course - missed doses risk treatment failure and resistance.
- Avoid amiodarone.
- Test for HBV before starting; monitor LFTs.
- Separate from antacids by 4 hours.
Sources
See how ledipasvir/sofosbuvir appears in NAPLEX-style questions
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