ivabradine(Corlanor)
Hyperpolarization-activated cyclic nucleotide-gated (HCN/If) channel blocker
Pronunciation
/aɪˈvæbrədiːn/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- ivabradine
- Brand names
- Corlanor
- Therapeutic class
- Hyperpolarization-activated cyclic nucleotide-gated (HCN/If) channel blocker
- Mechanism (summary)
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Clinical pearls
- Take with food; same time twice daily.
- Avoid grapefruit juice.
- Report slow heartbeat, irregular pulse, vision changes (brief bright spots = phosphenes; usually benign).
- Effective contraception required - teratogenic.
- Use is in addition to (not replacing) guideline beta-blocker therapy.
Sources
See how ivabradine appears in NAPLEX-style questions
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