isoniazid(INH, Nydrazid)
Antimycobacterial (mycolic acid synthesis inhibitor)
Pronunciation
/aɪsoʊˈnaɪəzɪd/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- isoniazid
- Brand names
- INH, Nydrazid
- Therapeutic class
- Antimycobacterial (mycolic acid synthesis inhibitor)
- Mechanism (summary)
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Clinical pearls
- Take on an empty stomach (1 h before or 2 h after food) for best absorption.
- Take pyridoxine (B6) daily to prevent neuropathy.
- Avoid alcohol completely.
- Report fatigue, nausea, RUQ pain, dark urine, jaundice.
- Avoid aged cheeses, red wine if you get headaches/flushing after meals.
Sources
See how isoniazid appears in NAPLEX-style questions
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