infliximab(Remicade, Inflectra, Renflexis)
Tumor necrosis factor (TNF) inhibitor (chimeric monoclonal antibody)
Pronunciation
/ɪnˈflɪksɪmæb/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- infliximab
- Brand names
- Remicade, Inflectra, Renflexis, Avsola
- Therapeutic class
- Tumor necrosis factor (TNF) inhibitor (chimeric monoclonal antibody)
- Mechanism (summary)
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Clinical pearls
- IV infusion in clinic; ~2-3 hour infusion.
- May be premedicated to prevent infusion reactions.
- Screen for latent TB and HBV before starting.
- No live vaccines.
- Often co-administered with methotrexate or azathioprine to reduce anti-drug antibodies.
Sources
See how infliximab appears in NAPLEX-style questions
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