glecaprevir/pibrentasvir(Mavyret)
HCV NS3/4A protease inhibitor + NS5A inhibitor (pan-genotypic DAA)
Pronunciation
/ɡlɛˈkæprəvɪr/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- glecaprevir/pibrentasvir
- Brand names
- Mavyret
- Therapeutic class
- HCV NS3/4A protease inhibitor + NS5A inhibitor (pan-genotypic DAA)
- Mechanism (summary)
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Clinical pearls
- Take ALL THREE TABLETS together once daily WITH FOOD.
- Pan-genotypic - works for all 6 HCV genotypes.
- Adhere to full course; missed doses risk failure/resistance.
- Avoid combined oral contraceptives (use IUD/progestin-only).
- Test for HBV before starting.
Sources
See how glecaprevir/pibrentasvir appears in NAPLEX-style questions
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