dolutegravir(Tivicay, Dovato (w/ 3TC), Triumeq (w/ ABC/3TC))
Integrase strand transfer inhibitor (INSTI)
Pronunciation
/doʊluːˈtɛɡrəvɪr/
International Phonetic Alphabet (IPA). Say it aloud once — you will remember it forever.
At a glance
- Generic name
- dolutegravir
- Brand names
- Tivicay, Dovato (w/ 3TC), Triumeq (w/ ABC/3TC)
- Therapeutic class
- Integrase strand transfer inhibitor (INSTI)
- Mechanism (summary)
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Clinical pearls
- Take once daily, with or without food.
- Separate from antacids/multivitamins (containing Ca, Mg, Al, Fe, Zn) by 2h before or 6h after.
- Report rash, fever, or symptoms of liver injury.
- Neural tube defect signal at conception (Tsepamo study) - shared decision-making for those who may become pregnant.
- ### NAPLEX practice notes
Related drugs in this class
Sources
See how dolutegravir appears in NAPLEX-style questions
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